comics I like

Daily comics

sinfest - recurring characters and themes (sometimes adult).
SMBC (Saturday Morning Breakfast Cereal) - hit or miss humor, sometimes with adult themes

Lunarbaboon - "a half man/half moon monkey trying to make sense of it all" -- a lot of middle aged parent perspective. Gently humorous.
Buttersafe - a bit of oddball humor, sometimes brilliant, sometimes mildly humorous

SLEIG: So Long To Everything, I Guess - a humorous and strange comic about a girl with psychic abilities
John Campbell's archive of Simon Veil's Pictures for Sad Children (the long, sad, strange story of Simone Veil and her comic)
Dresden Codak - dark science, drama, humor and beautiful colored drawings
Thermohalia - intriguing story of amphibians and robots
Nimona -- great story involving knights, science, magic and a special shape-shifting, amoral girl
Blue Milk Special - a funny (if sometimes a bit off-color) parody of the entire Star Wars universe of stories, focusing mostly but not solely upon the movies
Haven't browsed much yet in this list of 17 Fantastic Completed Webcomics to Binge-Read from Beginning to End

The Awkward Yeti, especially Gallbladder's Day
bouletcorp.com - fascinating stories like Kingdom Lost, the story of a wizard, a princess and a prince (but not the kind of story you might expect). Very well written and drawn.
JL8, about the young JLA (Justice League of America) members. I mean really young. Humorous and well drawn. Read from the beginning because there is a character arc.
Fredo & Pid'jin (irreverent, funny, sometimes a bit risque; love this one and this one)
Sarah Oleksyk's comics -- beautifully drawn, thoughtful explorations
RyanEstrada.com (Mystical Monkey comic (great punchline))
copper, a beautiful strip about a boy and his dog
The Gamer Cat - short, well-illustrated comics about a gamer cat
Hyperbole and a half - very cute, rough sketches in Microsoft paint accompanying brilliantly written comedic prose
My Cardboard Life

minus - quirky, moving, funny, long stories about a girl, minus, who has special powers (ended now :-()
Chuck and Beans - cute comic about a rabbit and a dog.
truckbearingkibble - very clever and beautifully drawn and colored. Unfortunately the original site is no longer on the internet. Especially see the Fossilwood strip from TruckBearingKibble
hatpire - by Becky Turpin - artfully and simply drawn, about the misadventures of a vampire in a tall hat. Ended now.

Port Sherry. Especially see Shoot for the Moon (found that very funny)
Pandyland - a bit crude, but well written and funny, sometimes poignant. See this one about a guy who is sleeping and dreaming and getting pranked by his buddies and this great comic about Fluffy.
Wandering Viola -- exquisitely drawn, thoughtful comics
Edmund Finney's Quest to find the meaning of life - funny and quirky and well-drawn with a distinctive style
the dog house diaries - stick figure comic but with a very different vibe. funny.
simulated comic product
amazingsuperpowers
odd-fish
nobody scores
ctrl-alt-del
far left side
dilbert
non-sequitur
subnormality - offbeat
Customer Servicer - incredibly off-the-wall, irreverent and surprisingly good storytelling about the employees of a 7-11 type of store. More recently the quality of humor has fallen off, alas.

Calvin and Hobbes --maybe the best comic ever. Great imagination paired with incredible artistry
Bloom County - wacky, irreverent; very funny
Peanuts by Charles Schultz -- this is the comic I grew up with
Prince Valiant - engaging story and wonderful artwork